Continuous Infusion
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Continuous infusion factor replacement is not a new therapy. It has been around since the 1970s. What makes continuous infusion exciting is that it can be taken out of the hospital and into the home by extending the therapy through qualified home infusion nurses. Now more than ever, when insurance costs continue to rise and hospitals are releasing patients earlier, home infusion provides a solution.
Continuous infusion uses a small ambulatory infusion pump to inject clotting factor constantly at a steady rate. The traditional bolus method injects larger quantities periodically (for example, twice a day), resulting in sub- and supra-therapeutic factor levels over the course of therapy.
The advantages of continuous infusion are most evident in cases of serious bleeds, pre- and post-operative use, and immune tolerance therapy. Continuous infusion allows for stable factor levels to circulate in the blood, resulting in better hemostasis versus traditional bolus therapy. Plus the cost savings can be dramatic.
Continuous infusion requires a local pharmacy, trained in the preparation of factor and adding it to infusion bags under clinically sanitary conditions. A specialized home infusion company such as Coram, working collaboratively with a patient’s physician and hospital, can provide continuous infusion in the home for the remainder of therapy. This includes daily pharmacy compounding, daily deliveries, pump administration, nursing, and close clinical monitoring. In addition to reducing costly hospital stays, continuous infusion at home reduces the cost of product by maintaining therapeutic levels and allows the patient to recuperate at home with family.
If you are interested in learning more about continuous infusion factor replacement, please email info@coramhemophilia.com. We will respond within 24 hours.